Description
Product Characteristics: This gene encodes a member of a family of proteins that feature C2H2-type zinc finger domains. The encoded protein is a transcriptional repressor that acts as an effector of transforming growth factor beta signaling. Activity of this protein may inhibit the growth of cancers, particularly pancreatic cancer. Alternative splicing results in multiple transcript variants.,KLF10,EGR-alpha,EGRA,TIEG,TIEG1,Epigenetics & Nuclear Signaling,Transcription Factors,Nuclear Receptor Signaling,Nuclear hormone receptors,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Growth factor,Cardiovascular,Heart,Hypertrophy,KLF10
Target Information: Kruppel-like zinc finger transcription factor, involved in TGFbeta-mediated signaling cascades to the regulation of pancreatic epithelial cell growth